Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA

The modified base 5-methylcytosine (m(5)C) is well studied in DNA, but investigations of its prevalence in cellular RNA have been largely confined to tRNA and rRNA. In animals, the two m(5)C methyltransferases NSUN2 and TRDMT1 are known to modify specific tRNAs and have roles in the control of cell...

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Detalles Bibliográficos
Autores principales: Squires, Jeffrey E., Patel, Hardip R., Nousch, Marco, Sibbritt, Tennille, Humphreys, David T., Parker, Brian J., Suter, Catherine M., Preiss, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367185/
https://www.ncbi.nlm.nih.gov/pubmed/22344696
http://dx.doi.org/10.1093/nar/gks144

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