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Structure of the bifunctional methyltransferase YcbY (RlmKL) that adds the m(7)G2069 and m(2)G2445 modifications in Escherichia coli 23S rRNA

The 23S rRNA nucleotide m(2)G2445 is highly conserved in bacteria, and in Escherichia coli this modification is added by the enzyme YcbY. With lengths of around 700 amino acids, YcbY orthologs are the largest rRNA methyltransferases identified in Gram-negative bacteria, and they appear to be fusions...

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Detalles Bibliográficos
Autores principales: Wang, Kai-Tuo, Desmolaize, Benoit, Nan, Jie, Zhang, Xiao-Wei, Li, Lan-Fen, Douthwaite, Stephen, Su, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367195/
https://www.ncbi.nlm.nih.gov/pubmed/22362734
http://dx.doi.org/10.1093/nar/gks160