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Crystal structures of the tRNA:m(2)G6 methyltransferase Trm14/TrmN from two domains of life

Methyltransferases (MTases) form a major class of tRNA-modifying enzymes needed for the proper functioning of tRNA. Recently, RNA MTases from the TrmN/Trm14 family that are present in Archaea, Bacteria and Eukaryota have been shown to specifically modify tRNA(Phe) at guanosine 6 in the tRNA acceptor...

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Detalles Bibliográficos
Autores principales:	Fislage, Marcus, Roovers, Martine, Tuszynska, Irina, Bujnicki, Janusz M., Droogmans, Louis, Versées, Wim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367198/ https://www.ncbi.nlm.nih.gov/pubmed/22362751 http://dx.doi.org/10.1093/nar/gks163

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