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DNA looping by FokI: the impact of twisting and bending rigidity on protein-induced looping dynamics

Protein-induced DNA looping is crucial for many genetic processes such as transcription, gene regulation and DNA replication. Here, we use tethered-particle motion to examine the impact of DNA bending and twisting rigidity on loop capture and release, using the restriction endonuclease FokI as a tes...

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Detalles Bibliográficos
Autores principales: Laurens, Niels, Rusling, David A., Pernstich, Christian, Brouwer, Ineke, Halford, Stephen E., Wuite, Gijs J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367208/
https://www.ncbi.nlm.nih.gov/pubmed/22373924
http://dx.doi.org/10.1093/nar/gks184