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Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India

Faecal specimens collected from two outbreaks of acute gastroenteritis that occurred in southern Mumbai, India in March and October, 2006 were tested for seven different enteric viruses. Among the 218 specimens tested, 95 (43.6%) were positive, 73 (76.8%) for a single virus and 22 (23.2%) for multip...

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Autores principales: Chitambar, Shobha, Gopalkrishna, Varanasi, Chhabra, Preeti, Patil, Pooja, Verma, Harsha, Lahon, Anismrita, Arora, Ritu, Tatte, Vaishali, Ranshing, Sujata, Dhale, Ganesh, Kolhapure, Rajendra, Tikute, Sanjay, Kulkarni, Jagannath, Bhardwaj, Renu, Akarte, Sulbha, Pawar, Sashikant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367285/
https://www.ncbi.nlm.nih.gov/pubmed/22690171
http://dx.doi.org/10.3390/ijerph9030895
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author Chitambar, Shobha
Gopalkrishna, Varanasi
Chhabra, Preeti
Patil, Pooja
Verma, Harsha
Lahon, Anismrita
Arora, Ritu
Tatte, Vaishali
Ranshing, Sujata
Dhale, Ganesh
Kolhapure, Rajendra
Tikute, Sanjay
Kulkarni, Jagannath
Bhardwaj, Renu
Akarte, Sulbha
Pawar, Sashikant
author_facet Chitambar, Shobha
Gopalkrishna, Varanasi
Chhabra, Preeti
Patil, Pooja
Verma, Harsha
Lahon, Anismrita
Arora, Ritu
Tatte, Vaishali
Ranshing, Sujata
Dhale, Ganesh
Kolhapure, Rajendra
Tikute, Sanjay
Kulkarni, Jagannath
Bhardwaj, Renu
Akarte, Sulbha
Pawar, Sashikant
author_sort Chitambar, Shobha
collection PubMed
description Faecal specimens collected from two outbreaks of acute gastroenteritis that occurred in southern Mumbai, India in March and October, 2006 were tested for seven different enteric viruses. Among the 218 specimens tested, 95 (43.6%) were positive, 73 (76.8%) for a single virus and 22 (23.2%) for multiple viruses. Single viral infections in both, March and October showed predominance of enterovirus (EV, 33.3% and 40%) and rotavirus A (RVA, 33.3% and 25%). The other viruses detected in these months were norovirus (NoV, 12.1% and 10%), rotavirus B (RVB, 12.1% and 10%), enteric adenovirus (AdV, 6.1% and 7.5%), Aichivirus (AiV, 3% and 7.5%) and human astrovirus (HAstV, 3% and 0%). Mixed viral infections were largely represented by two viruses (84.6% and 88.9%), a small proportion showed presence of three (7.7% and 11%) and four (7.7% and 0%) viruses in the two outbreaks. Genotyping of the viruses revealed predominance of RVA G2P[4], RVB G2 (Indian Bangladeshi lineage), NoV GII.4, AdV-40, HAstV-8 and AiV B types. VP1/2A junction region based genotyping showed presence of 11 different serotypes of EVs. Although no virus was detected in the tested water samples, examination of both water and sewage pipelines in gastroenteritis affected localities indicated leakages and possibility of contamination of drinking water with sewage water. Coexistence of multiple enteric viruses during the two outbreaks of gastroenteritis emphasizes the need to expand such investigations to other parts of India.
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spelling pubmed-33672852012-06-11 Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India Chitambar, Shobha Gopalkrishna, Varanasi Chhabra, Preeti Patil, Pooja Verma, Harsha Lahon, Anismrita Arora, Ritu Tatte, Vaishali Ranshing, Sujata Dhale, Ganesh Kolhapure, Rajendra Tikute, Sanjay Kulkarni, Jagannath Bhardwaj, Renu Akarte, Sulbha Pawar, Sashikant Int J Environ Res Public Health Article Faecal specimens collected from two outbreaks of acute gastroenteritis that occurred in southern Mumbai, India in March and October, 2006 were tested for seven different enteric viruses. Among the 218 specimens tested, 95 (43.6%) were positive, 73 (76.8%) for a single virus and 22 (23.2%) for multiple viruses. Single viral infections in both, March and October showed predominance of enterovirus (EV, 33.3% and 40%) and rotavirus A (RVA, 33.3% and 25%). The other viruses detected in these months were norovirus (NoV, 12.1% and 10%), rotavirus B (RVB, 12.1% and 10%), enteric adenovirus (AdV, 6.1% and 7.5%), Aichivirus (AiV, 3% and 7.5%) and human astrovirus (HAstV, 3% and 0%). Mixed viral infections were largely represented by two viruses (84.6% and 88.9%), a small proportion showed presence of three (7.7% and 11%) and four (7.7% and 0%) viruses in the two outbreaks. Genotyping of the viruses revealed predominance of RVA G2P[4], RVB G2 (Indian Bangladeshi lineage), NoV GII.4, AdV-40, HAstV-8 and AiV B types. VP1/2A junction region based genotyping showed presence of 11 different serotypes of EVs. Although no virus was detected in the tested water samples, examination of both water and sewage pipelines in gastroenteritis affected localities indicated leakages and possibility of contamination of drinking water with sewage water. Coexistence of multiple enteric viruses during the two outbreaks of gastroenteritis emphasizes the need to expand such investigations to other parts of India. MDPI 2012-03-14 2012-03 /pmc/articles/PMC3367285/ /pubmed/22690171 http://dx.doi.org/10.3390/ijerph9030895 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Chitambar, Shobha
Gopalkrishna, Varanasi
Chhabra, Preeti
Patil, Pooja
Verma, Harsha
Lahon, Anismrita
Arora, Ritu
Tatte, Vaishali
Ranshing, Sujata
Dhale, Ganesh
Kolhapure, Rajendra
Tikute, Sanjay
Kulkarni, Jagannath
Bhardwaj, Renu
Akarte, Sulbha
Pawar, Sashikant
Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India
title Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India
title_full Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India
title_fullStr Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India
title_full_unstemmed Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India
title_short Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India
title_sort diversity in the enteric viruses detected in outbreaks of gastroenteritis from mumbai, western india
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367285/
https://www.ncbi.nlm.nih.gov/pubmed/22690171
http://dx.doi.org/10.3390/ijerph9030895
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