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Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India
Faecal specimens collected from two outbreaks of acute gastroenteritis that occurred in southern Mumbai, India in March and October, 2006 were tested for seven different enteric viruses. Among the 218 specimens tested, 95 (43.6%) were positive, 73 (76.8%) for a single virus and 22 (23.2%) for multip...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367285/ https://www.ncbi.nlm.nih.gov/pubmed/22690171 http://dx.doi.org/10.3390/ijerph9030895 |
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author | Chitambar, Shobha Gopalkrishna, Varanasi Chhabra, Preeti Patil, Pooja Verma, Harsha Lahon, Anismrita Arora, Ritu Tatte, Vaishali Ranshing, Sujata Dhale, Ganesh Kolhapure, Rajendra Tikute, Sanjay Kulkarni, Jagannath Bhardwaj, Renu Akarte, Sulbha Pawar, Sashikant |
author_facet | Chitambar, Shobha Gopalkrishna, Varanasi Chhabra, Preeti Patil, Pooja Verma, Harsha Lahon, Anismrita Arora, Ritu Tatte, Vaishali Ranshing, Sujata Dhale, Ganesh Kolhapure, Rajendra Tikute, Sanjay Kulkarni, Jagannath Bhardwaj, Renu Akarte, Sulbha Pawar, Sashikant |
author_sort | Chitambar, Shobha |
collection | PubMed |
description | Faecal specimens collected from two outbreaks of acute gastroenteritis that occurred in southern Mumbai, India in March and October, 2006 were tested for seven different enteric viruses. Among the 218 specimens tested, 95 (43.6%) were positive, 73 (76.8%) for a single virus and 22 (23.2%) for multiple viruses. Single viral infections in both, March and October showed predominance of enterovirus (EV, 33.3% and 40%) and rotavirus A (RVA, 33.3% and 25%). The other viruses detected in these months were norovirus (NoV, 12.1% and 10%), rotavirus B (RVB, 12.1% and 10%), enteric adenovirus (AdV, 6.1% and 7.5%), Aichivirus (AiV, 3% and 7.5%) and human astrovirus (HAstV, 3% and 0%). Mixed viral infections were largely represented by two viruses (84.6% and 88.9%), a small proportion showed presence of three (7.7% and 11%) and four (7.7% and 0%) viruses in the two outbreaks. Genotyping of the viruses revealed predominance of RVA G2P[4], RVB G2 (Indian Bangladeshi lineage), NoV GII.4, AdV-40, HAstV-8 and AiV B types. VP1/2A junction region based genotyping showed presence of 11 different serotypes of EVs. Although no virus was detected in the tested water samples, examination of both water and sewage pipelines in gastroenteritis affected localities indicated leakages and possibility of contamination of drinking water with sewage water. Coexistence of multiple enteric viruses during the two outbreaks of gastroenteritis emphasizes the need to expand such investigations to other parts of India. |
format | Online Article Text |
id | pubmed-3367285 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-33672852012-06-11 Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India Chitambar, Shobha Gopalkrishna, Varanasi Chhabra, Preeti Patil, Pooja Verma, Harsha Lahon, Anismrita Arora, Ritu Tatte, Vaishali Ranshing, Sujata Dhale, Ganesh Kolhapure, Rajendra Tikute, Sanjay Kulkarni, Jagannath Bhardwaj, Renu Akarte, Sulbha Pawar, Sashikant Int J Environ Res Public Health Article Faecal specimens collected from two outbreaks of acute gastroenteritis that occurred in southern Mumbai, India in March and October, 2006 were tested for seven different enteric viruses. Among the 218 specimens tested, 95 (43.6%) were positive, 73 (76.8%) for a single virus and 22 (23.2%) for multiple viruses. Single viral infections in both, March and October showed predominance of enterovirus (EV, 33.3% and 40%) and rotavirus A (RVA, 33.3% and 25%). The other viruses detected in these months were norovirus (NoV, 12.1% and 10%), rotavirus B (RVB, 12.1% and 10%), enteric adenovirus (AdV, 6.1% and 7.5%), Aichivirus (AiV, 3% and 7.5%) and human astrovirus (HAstV, 3% and 0%). Mixed viral infections were largely represented by two viruses (84.6% and 88.9%), a small proportion showed presence of three (7.7% and 11%) and four (7.7% and 0%) viruses in the two outbreaks. Genotyping of the viruses revealed predominance of RVA G2P[4], RVB G2 (Indian Bangladeshi lineage), NoV GII.4, AdV-40, HAstV-8 and AiV B types. VP1/2A junction region based genotyping showed presence of 11 different serotypes of EVs. Although no virus was detected in the tested water samples, examination of both water and sewage pipelines in gastroenteritis affected localities indicated leakages and possibility of contamination of drinking water with sewage water. Coexistence of multiple enteric viruses during the two outbreaks of gastroenteritis emphasizes the need to expand such investigations to other parts of India. MDPI 2012-03-14 2012-03 /pmc/articles/PMC3367285/ /pubmed/22690171 http://dx.doi.org/10.3390/ijerph9030895 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Chitambar, Shobha Gopalkrishna, Varanasi Chhabra, Preeti Patil, Pooja Verma, Harsha Lahon, Anismrita Arora, Ritu Tatte, Vaishali Ranshing, Sujata Dhale, Ganesh Kolhapure, Rajendra Tikute, Sanjay Kulkarni, Jagannath Bhardwaj, Renu Akarte, Sulbha Pawar, Sashikant Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India |
title | Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India |
title_full | Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India |
title_fullStr | Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India |
title_full_unstemmed | Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India |
title_short | Diversity in the Enteric Viruses Detected in Outbreaks of Gastroenteritis from Mumbai, Western India |
title_sort | diversity in the enteric viruses detected in outbreaks of gastroenteritis from mumbai, western india |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367285/ https://www.ncbi.nlm.nih.gov/pubmed/22690171 http://dx.doi.org/10.3390/ijerph9030895 |
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