Cargando…
Genetic recombination is directed away from functional genomic elements in mice
Genetic recombination occurs during meiosis, the key developmental program of gametogenesis. Recombination in mammals has been recently linked to the activity of a histone H3 methyl-transferase, PRDM9(1–6), the product of the only known speciation gene in mammals(7). PRDM9 is thought to determine th...
Autores principales: | Brick, Kevin, Smagulova, Fatima, Khil, Pavel, Camerini-Otero, R. Daniel, Petukhova, Galina V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367396/ https://www.ncbi.nlm.nih.gov/pubmed/22660327 http://dx.doi.org/10.1038/nature11089 |
Ejemplares similares
-
Sensitive mapping of recombination hotspots using sequencing-based detection of ssDNA
por: Khil, Pavel P., et al.
Publicado: (2012) -
The evolutionary turnover of recombination hot spots contributes to speciation in mice
por: Smagulova, Fatima, et al.
Publicado: (2016) -
Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele
por: Smagulova, Fatima, et al.
Publicado: (2013) -
Extensive sex differences at the initiation of genetic recombination
por: Brick, Kevin, et al.
Publicado: (2018) -
Interrogating the Functions of PRDM9 Domains in Meiosis
por: Thibault-Sennett, Sarah, et al.
Publicado: (2018)