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Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer
This report documents a case of T cell lymphoma manifesting only with a conjunctival mass. A 67-year-old man underwent a diagnostic punch biopsy, histopathological examination, and immunohistochemical study for a pink-yellow colored mass infiltrating the bulbar conjunctiva in the lower fornix of the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367434/ https://www.ncbi.nlm.nih.gov/pubmed/22693420 http://dx.doi.org/10.2147/OPTH.S28499 |
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author | Isola, Vincenzo Mazzacane, Danilo Defelice, Noemi D’Amico, Antonio Dezza, Laura Marti, Antonio Pece, Alfredo |
author_facet | Isola, Vincenzo Mazzacane, Danilo Defelice, Noemi D’Amico, Antonio Dezza, Laura Marti, Antonio Pece, Alfredo |
author_sort | Isola, Vincenzo |
collection | PubMed |
description | This report documents a case of T cell lymphoma manifesting only with a conjunctival mass. A 67-year-old man underwent a diagnostic punch biopsy, histopathological examination, and immunohistochemical study for a pink-yellow colored mass infiltrating the bulbar conjunctiva in the lower fornix of the eyelid. A biopsy specimen of the conjunctival mass was found histopathologically to be a malignant T cell lymphoma. Systemic involvement was diagnosed within four weeks after the initial diagnosis by computed tomography, showing evidence of extension at the level of the ethmoidal cells, optic nerve, periorbital tissue, and pancreas. T cell lymphoma of the conjunctiva as a primary manifestation of systemic cancer is an uncommon entity. Punch biopsy may be the first diagnostic pathway useful to initiate a search for systemic involvement of a malignant lymphoid tumor of T cell lineage. |
format | Online Article Text |
id | pubmed-3367434 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-33674342012-06-12 Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer Isola, Vincenzo Mazzacane, Danilo Defelice, Noemi D’Amico, Antonio Dezza, Laura Marti, Antonio Pece, Alfredo Clin Ophthalmol Case Report This report documents a case of T cell lymphoma manifesting only with a conjunctival mass. A 67-year-old man underwent a diagnostic punch biopsy, histopathological examination, and immunohistochemical study for a pink-yellow colored mass infiltrating the bulbar conjunctiva in the lower fornix of the eyelid. A biopsy specimen of the conjunctival mass was found histopathologically to be a malignant T cell lymphoma. Systemic involvement was diagnosed within four weeks after the initial diagnosis by computed tomography, showing evidence of extension at the level of the ethmoidal cells, optic nerve, periorbital tissue, and pancreas. T cell lymphoma of the conjunctiva as a primary manifestation of systemic cancer is an uncommon entity. Punch biopsy may be the first diagnostic pathway useful to initiate a search for systemic involvement of a malignant lymphoid tumor of T cell lineage. Dove Medical Press 2012 2012-05-21 /pmc/articles/PMC3367434/ /pubmed/22693420 http://dx.doi.org/10.2147/OPTH.S28499 Text en © 2012 Isola et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Case Report Isola, Vincenzo Mazzacane, Danilo Defelice, Noemi D’Amico, Antonio Dezza, Laura Marti, Antonio Pece, Alfredo Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer |
title | Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer |
title_full | Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer |
title_fullStr | Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer |
title_full_unstemmed | Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer |
title_short | Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer |
title_sort | malignant conjunctival t cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367434/ https://www.ncbi.nlm.nih.gov/pubmed/22693420 http://dx.doi.org/10.2147/OPTH.S28499 |
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