Cargando…

Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer

This report documents a case of T cell lymphoma manifesting only with a conjunctival mass. A 67-year-old man underwent a diagnostic punch biopsy, histopathological examination, and immunohistochemical study for a pink-yellow colored mass infiltrating the bulbar conjunctiva in the lower fornix of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Isola, Vincenzo, Mazzacane, Danilo, Defelice, Noemi, D’Amico, Antonio, Dezza, Laura, Marti, Antonio, Pece, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367434/
https://www.ncbi.nlm.nih.gov/pubmed/22693420
http://dx.doi.org/10.2147/OPTH.S28499
_version_ 1782234849156792320
author Isola, Vincenzo
Mazzacane, Danilo
Defelice, Noemi
D’Amico, Antonio
Dezza, Laura
Marti, Antonio
Pece, Alfredo
author_facet Isola, Vincenzo
Mazzacane, Danilo
Defelice, Noemi
D’Amico, Antonio
Dezza, Laura
Marti, Antonio
Pece, Alfredo
author_sort Isola, Vincenzo
collection PubMed
description This report documents a case of T cell lymphoma manifesting only with a conjunctival mass. A 67-year-old man underwent a diagnostic punch biopsy, histopathological examination, and immunohistochemical study for a pink-yellow colored mass infiltrating the bulbar conjunctiva in the lower fornix of the eyelid. A biopsy specimen of the conjunctival mass was found histopathologically to be a malignant T cell lymphoma. Systemic involvement was diagnosed within four weeks after the initial diagnosis by computed tomography, showing evidence of extension at the level of the ethmoidal cells, optic nerve, periorbital tissue, and pancreas. T cell lymphoma of the conjunctiva as a primary manifestation of systemic cancer is an uncommon entity. Punch biopsy may be the first diagnostic pathway useful to initiate a search for systemic involvement of a malignant lymphoid tumor of T cell lineage.
format Online
Article
Text
id pubmed-3367434
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Dove Medical Press
record_format MEDLINE/PubMed
spelling pubmed-33674342012-06-12 Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer Isola, Vincenzo Mazzacane, Danilo Defelice, Noemi D’Amico, Antonio Dezza, Laura Marti, Antonio Pece, Alfredo Clin Ophthalmol Case Report This report documents a case of T cell lymphoma manifesting only with a conjunctival mass. A 67-year-old man underwent a diagnostic punch biopsy, histopathological examination, and immunohistochemical study for a pink-yellow colored mass infiltrating the bulbar conjunctiva in the lower fornix of the eyelid. A biopsy specimen of the conjunctival mass was found histopathologically to be a malignant T cell lymphoma. Systemic involvement was diagnosed within four weeks after the initial diagnosis by computed tomography, showing evidence of extension at the level of the ethmoidal cells, optic nerve, periorbital tissue, and pancreas. T cell lymphoma of the conjunctiva as a primary manifestation of systemic cancer is an uncommon entity. Punch biopsy may be the first diagnostic pathway useful to initiate a search for systemic involvement of a malignant lymphoid tumor of T cell lineage. Dove Medical Press 2012 2012-05-21 /pmc/articles/PMC3367434/ /pubmed/22693420 http://dx.doi.org/10.2147/OPTH.S28499 Text en © 2012 Isola et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Case Report
Isola, Vincenzo
Mazzacane, Danilo
Defelice, Noemi
D’Amico, Antonio
Dezza, Laura
Marti, Antonio
Pece, Alfredo
Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer
title Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer
title_full Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer
title_fullStr Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer
title_full_unstemmed Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer
title_short Malignant conjunctival T cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer
title_sort malignant conjunctival t cell lymphoma diagnosed by punch biopsy as a primary manifestation of systemic cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367434/
https://www.ncbi.nlm.nih.gov/pubmed/22693420
http://dx.doi.org/10.2147/OPTH.S28499
work_keys_str_mv AT isolavincenzo malignantconjunctivaltcelllymphomadiagnosedbypunchbiopsyasaprimarymanifestationofsystemiccancer
AT mazzacanedanilo malignantconjunctivaltcelllymphomadiagnosedbypunchbiopsyasaprimarymanifestationofsystemiccancer
AT defelicenoemi malignantconjunctivaltcelllymphomadiagnosedbypunchbiopsyasaprimarymanifestationofsystemiccancer
AT damicoantonio malignantconjunctivaltcelllymphomadiagnosedbypunchbiopsyasaprimarymanifestationofsystemiccancer
AT dezzalaura malignantconjunctivaltcelllymphomadiagnosedbypunchbiopsyasaprimarymanifestationofsystemiccancer
AT martiantonio malignantconjunctivaltcelllymphomadiagnosedbypunchbiopsyasaprimarymanifestationofsystemiccancer
AT pecealfredo malignantconjunctivaltcelllymphomadiagnosedbypunchbiopsyasaprimarymanifestationofsystemiccancer