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Chemical coupling of thiolated chitosan to preformed liposomes improves mucoadhesive properties

AIM: To develop mucoadhesive liposomes by anchoring the polymer chitosan-thioglycolic acid (chitosan-TGA) to the liposomal surface to target intestinal mucosal membranes. METHODS: Liposomes consisting of phosphatidylcholine (POPC) and a maleimide-functionalized lipid were incubated with chitosan-TGA...

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Detalles Bibliográficos
Autores principales:	Gradauer, Kerstin, Vonach, Caroline, Leitinger, Gerd, Kolb, Dagmar, Fröhlich, Eleonore, Roblegg, Eva, Bernkop-Schnürch, Andreas, Prassl, Ruth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367495/ https://www.ncbi.nlm.nih.gov/pubmed/22679365 http://dx.doi.org/10.2147/IJN.S29980

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