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Regulation of Circadian Behavior and Metabolism by Rev-erbα and Rev-erbβ
The circadian clock acts at the genomic level to coordinate internal behavioral and physiologic rhythms via the CLOCK-BMAL transcriptional heterodimer. Although the nuclear receptors REV-ERBα and β have been proposed to form an accessory feedback loop that contributes to clock function(1,2), their p...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367514/ https://www.ncbi.nlm.nih.gov/pubmed/22460952 http://dx.doi.org/10.1038/nature11048 |