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Analytic Markovian Rates for Generalized Protein Structure Evolution
A general understanding of the complex phenomenon of protein evolution requires the accurate description of the constraints that define the sub-space of proteins with mutations that do not appreciably reduce the fitness of the organism. Such constraints can have multiple origins, in this work we pre...
Autores principales: | Coluzza, Ivan, MacDonald, James T., Sadowski, Michael I., Taylor, William R., Goldstein, Richard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367531/ https://www.ncbi.nlm.nih.gov/pubmed/22693543 http://dx.doi.org/10.1371/journal.pone.0034228 |
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