Rifampin-resistant Meningococcal Disease

Rifampin-resistant meningococcal disease occurred in a child who had completed rifampin chemoprophylaxis for exposure to a sibling with meningococcemia. Susceptibility testing of 331 case isolates found only 1 other case of rifampin-resistant disease in Minnesota, USA, during 11 years of statewide s...

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Detalles Bibliográficos
Autores principales: Rainbow, Jean, Cebelinski, Elizabeth, Bartkus, Joanne, Glennen, Anita, Boxrud, Dave, Lynfield, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2005
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367591/
https://www.ncbi.nlm.nih.gov/pubmed/15963302
http://dx.doi.org/10.3201/eid1106.050143
Descripción
Sumario:Rifampin-resistant meningococcal disease occurred in a child who had completed rifampin chemoprophylaxis for exposure to a sibling with meningococcemia. Susceptibility testing of 331 case isolates found only 1 other case of rifampin-resistant disease in Minnesota, USA, during 11 years of statewide surveillance. Point mutations in the RNA polymerase β subunit (rpoB) gene were found in isolates from each rifampin-resistant case-patient.

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