Covalent Protein Modification with ISG15 via a Conserved Cysteine in the Hinge Region

The ubiquitin-like protein ISG15 (interferon-stimulated gene of 15 kDa) is strongly induced by type I interferons and displays antiviral activity. As other ubiquitin-like proteins (Ubls), ISG15 is post-translationally conjugated to substrate proteins by an isopeptide bond between the C-terminal glyc...

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Detalles Bibliográficos
Autores principales: Bade, Veronika N., Nickels, Jochen, Keusekotten, Kirstin, Praefcke, Gerrit J. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367918/
https://www.ncbi.nlm.nih.gov/pubmed/22693631
http://dx.doi.org/10.1371/journal.pone.0038294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367918/
https://www.ncbi.nlm.nih.gov/pubmed/22693631
http://dx.doi.org/10.1371/journal.pone.0038294

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