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Hierarchical Control on Polyene Macrolide Biosynthesis: PimR Modulates Pimaricin Production via the PAS-LuxR Transcriptional Activator PimM
Control of polyene macrolide production in Streptomyces natalensis is mediated by the transcriptional activator PimR. This regulator combines an N-terminal domain corresponding to the Streptomyces antibiotic regulatory protein (SARP) family of transcriptional activators with a C-terminal half homolo...
Autores principales: | Santos-Aberturas, Javier, Vicente, Cláudia M., Payero, Tamara D., Martín-Sánchez, Lara, Cañibano, Carmen, Martín, Juan F., Aparicio, Jesús F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367932/ https://www.ncbi.nlm.nih.gov/pubmed/22693644 http://dx.doi.org/10.1371/journal.pone.0038536 |
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