Leptin restores adult hippocampal neurogenesis suppressed by chronic unpredictable stress and reverses glucocorticoid-induced inhibition of GSK3β/β-catenin signaling

Stress and glucocorticoid stress hormones inhibit neurogenesis, whereas antidepressants increase neurogenesis and block stress-induced decrease of neurogenesis. Our previous studies have shown leptin, an adipocyte-derived hormone with antidepressant-like properties (1), promotes baseline neurogenesi...

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Detalles Bibliográficos
Autores principales: Garza, Jacob C., Guo, Ming, Zhang, Wei, Lu, Xin-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368076/
https://www.ncbi.nlm.nih.gov/pubmed/22182938
http://dx.doi.org/10.1038/mp.2011.161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368076/
https://www.ncbi.nlm.nih.gov/pubmed/22182938
http://dx.doi.org/10.1038/mp.2011.161

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