Hyperuricemic Renal Failure in Nonhematologic Solid Tumors: A Case Report and Review of the Literature

Tumor lysis syndrome (TLS) is an oncologic emergency that is caused by massive tumor cell lysis. It is commonly associated with hematological cancers like leukemia and lymphoma and uncommonly with solid nonhematologic tumors as well. However, spontaneous tumor lysis syndrome (STLS) without any cytot...

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Detalles Bibliográficos
Autores principales: Saini, Neeraj, Pyo Lee, Kyeong, Jha, Smita, Patel, Sanket, Bonthu, Neelima, Kansagra, Ankit, Bhatia, Ashmeet, Martinez, Sandra E., Patel, Jaymin, Altamimi, Sarah, Ghotb, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368227/
https://www.ncbi.nlm.nih.gov/pubmed/22693518
http://dx.doi.org/10.1155/2012/314056
Descripción
Sumario:Tumor lysis syndrome (TLS) is an oncologic emergency that is caused by massive tumor cell lysis. It is commonly associated with hematological cancers like leukemia and lymphoma and uncommonly with solid nonhematologic tumors as well. However, spontaneous tumor lysis syndrome (STLS) without any cytotoxic chemotherapy rarely occurs in solid tumors. We describe a case of STLS in a metastatic adenocarcinoma of unknown primary and review the literature of STLS in solid non-hematologic tumors to identify various risk factors for pathogenesis of this entity.

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