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Triarylmethanes, a New Class of Cx50 Inhibitors
The paucity of specific pharmacological agents has been a major impediment for delineating the roles of gap junction (GJ) channels formed by connexin proteins in physiology and pathophysiology. Here, we used the selective optimization of side activities (SOSA) approach, which has led to the design o...
Autores principales: | Bodendiek, Silke B., Rubinos, Clio, Trelles, Maria Pilar, Coleman, Nichole, Jenkins, David Paul, Wulff, Heike, Srinivas, Miduturu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368247/ https://www.ncbi.nlm.nih.gov/pubmed/22685432 http://dx.doi.org/10.3389/fphar.2012.00106 |
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