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Waves of Retrotransposon Expansion Remodel Genome Organization and CTCF Binding in Multiple Mammalian Lineages
CTCF-binding locations represent regulatory sequences that are highly constrained over the course of evolution. To gain insight into how these DNA elements are conserved and spread through the genome, we defined the full spectrum of CTCF-binding sites, including a 33/34-mer motif, and identified ove...
Autores principales: | Schmidt, Dominic, Schwalie, Petra C., Wilson, Michael D., Ballester, Benoit, Gonçalves, Ângela, Kutter, Claudia, Brown, Gordon D., Marshall, Aileen, Flicek, Paul, Odom, Duncan T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368268/ https://www.ncbi.nlm.nih.gov/pubmed/22244452 http://dx.doi.org/10.1016/j.cell.2011.11.058 |
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