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Codon Deviation Coefficient: a novel measure for estimating codon usage bias and its statistical significance

BACKGROUND: Genetic mutation, selective pressure for translational efficiency and accuracy, level of gene expression, and protein function through natural selection are all believed to lead to codon usage bias (CUB). Therefore, informative measurement of CUB is of fundamental importance to making in...

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Detalles Bibliográficos
Autores principales: Zhang, Zhang, Li, Jun, Cui, Peng, Ding, Feng, Li, Ang, Townsend, Jeffrey P, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368730/
https://www.ncbi.nlm.nih.gov/pubmed/22435713
http://dx.doi.org/10.1186/1471-2105-13-43