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Codon Deviation Coefficient: a novel measure for estimating codon usage bias and its statistical significance
BACKGROUND: Genetic mutation, selective pressure for translational efficiency and accuracy, level of gene expression, and protein function through natural selection are all believed to lead to codon usage bias (CUB). Therefore, informative measurement of CUB is of fundamental importance to making in...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368730/ https://www.ncbi.nlm.nih.gov/pubmed/22435713 http://dx.doi.org/10.1186/1471-2105-13-43 |