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Cell number and transfection volume dependent peptide nucleic acid antisense activity by cationic delivery methods

Efficient intracellular delivery is essential for high activity of nucleic acids based therapeutics, including antisense agents. Several strategies have been developed and practically all rely on auxiliary transfection reagents such as cationic lipids, cationic polymers and cell penetrating peptides...

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Detalles Bibliográficos
Autores principales: Llovera, Laia, Berthold, Peter, Nielsen, Peter E., Shiraishi, Takehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368813/
https://www.ncbi.nlm.nih.gov/pubmed/22679530
http://dx.doi.org/10.4161/adna.19906