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Characterization of 4-HNE Modified L-FABP Reveals Alterations in Structural and Functional Dynamics

4-Hydroxynonenal (4-HNE) is a reactive α,β-unsaturated aldehyde produced during oxidative stress and subsequent lipid peroxidation of polyunsaturated fatty acids. The reactivity of 4-HNE towards DNA and nucleophilic amino acids has been well established. In this report, using proteomic approaches, l...

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Detalles Bibliográficos
Autores principales:	Smathers, Rebecca L., Fritz, Kristofer S., Galligan, James J., Shearn, Colin T., Reigan, Philip, Marks, Michael J., Petersen, Dennis R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368874/ https://www.ncbi.nlm.nih.gov/pubmed/22701647 http://dx.doi.org/10.1371/journal.pone.0038459

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