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The Effect of Pre-Analytical Variability on the Measurement of MRM-MS-Based Mid- to High-Abundance Plasma Protein Biomarkers and a Panel of Cytokines

Blood sample processing and handling can have a significant impact on the stability and levels of proteins measured in biomarker studies. Such pre-analytical variability needs to be well understood in the context of the different proteomics platforms available for biomarker discovery and validation....

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Detalles Bibliográficos
Autores principales:	Aguilar-Mahecha, Adriana, Kuzyk, Michael A., Domanski, Dominik, Borchers, Christoph H., Basik, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368926/ https://www.ncbi.nlm.nih.gov/pubmed/22701622 http://dx.doi.org/10.1371/journal.pone.0038290

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