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Tissue-Specific Responses of IGF-1/Insulin and mTOR Signaling in Calorie Restricted Rats
Moderate calorie restriction (CR) (∼60% of ad libitum, AL, intake) has been associated with numerous favorable physiological outcomes in many species, and the insulin/IGF-1 and mTOR signaling pathways have each been proposed as potential mediators for many of CR's bioeffects. However, few studi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368930/ https://www.ncbi.nlm.nih.gov/pubmed/22701721 http://dx.doi.org/10.1371/journal.pone.0038835 |