Active Zone Protein Bassoon Co-Localizes with Presynaptic Calcium Channel, Modifies Channel Function, and Recovers from Aging Related Loss by Exercise

The P/Q-type voltage-dependent calcium channels (VDCCs) are essential for synaptic transmission at adult mammalian neuromuscular junctions (NMJs); however, the subsynaptic location of VDCCs relative to active zones in rodent NMJs, and the functional modification of VDCCs by the interaction with acti...

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Detalles Bibliográficos
Autores principales: Nishimune, Hiroshi, Numata, Tomohiro, Chen, Jie, Aoki, Yudai, Wang, Yonghong, Starr, Miranda P., Mori, Yasuo, Stanford, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368936/
https://www.ncbi.nlm.nih.gov/pubmed/22701595
http://dx.doi.org/10.1371/journal.pone.0038029

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