Proteomic Analysis of Neisseria gonorrhoeae Biofilms Shows Shift to Anaerobic Respiration and Changes in Nutrient Transport and Outermembrane Proteins

Neisseria gonorrhoeae, the causative agent of gonorrhea, can form biofilms in vitro and in vivo. In biofilms, the organism is more resistant to antibiotic treatment and can serve as a reservoir for chronic infection. We have used stable isotope labeling by amino acids in cell culture (SILAC) to comp...

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Detalles Bibliográficos
Autores principales: Phillips, Nancy J., Steichen, Christopher T., Schilling, Birgit, Post, Deborah M. B., Niles, Richard K., Bair, Thomas B., Falsetta, Megan L., Apicella, Michael A., Gibson, Bradford W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368942/
https://www.ncbi.nlm.nih.gov/pubmed/22701624
http://dx.doi.org/10.1371/journal.pone.0038303

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