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Exploiting sparseness in de novo genome assembly

BACKGROUND: The very large memory requirements for the construction of assembly graphs for de novo genome assembly limit current algorithms to super-computing environments. METHODS: In this paper, we demonstrate that constructing a sparse assembly graph which stores only a small fraction of the obse...

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Detalles Bibliográficos
Autores principales:	Ye, Chengxi, Ma, Zhanshan Sam, Cannon, Charles H, Pop, Mihai, Yu, Douglas W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369186/ https://www.ncbi.nlm.nih.gov/pubmed/22537038 http://dx.doi.org/10.1186/1471-2105-13-S6-S1

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