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Large-scale survey for novel genotypes of Plasmodium falciparum chloroquine-resistance gene pfcrt

BACKGROUND: In Plasmodium falciparum, resistance to chloroquine (CQ) is conferred by a K to T mutation at amino acid position 76 (K76T) in the P. falciparum CQ transporter (PfCRT). To date, at least 15 pfcrt genotypes, which are represented by combinations of five amino acids at positions 72-76, hav...

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Detalles Bibliográficos
Autores principales:	Takahashi, Nobuyuki, Tanabe, Kazuyuki, Tsukahara, Takahiro, Dzodzomenyo, Mawuli, Dysoley, Lek, Khamlome, Boualam, Sattabongkot, Jetsumon, Nakamura, Masatoshi, Sakurai, Miki, Kobayashi, Jun, Kaneko, Akira, Endo, Hiroyoshi, Hombhanje, Francis, Tsuboi, Takafumi, Mita, Toshihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369212/ https://www.ncbi.nlm.nih.gov/pubmed/22453078 http://dx.doi.org/10.1186/1475-2875-11-92

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