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Physiopathology of Bone Modifications in β-Thalassemia
β-thalassemia major (βTM) or Cooley anemia is characterized by significantly reduced or absent synthesis of β-globin chains, which induces important pathologic consequences including hemolytic anemia, altered erythropoiesis, and bone marrow overstimulation. The pathogenesis of bone changes in patien...
Autores principales: | Perisano, Carlo, Marzetti, Emanuele, Spinelli, Maria Silvia, Callà, Cinzia Anna Maria, Graci, Calogero, Maccauro, Giulio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369393/ https://www.ncbi.nlm.nih.gov/pubmed/22693660 http://dx.doi.org/10.1155/2012/320737 |
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