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Subtle Recognition of 14-Base Pair DNA Sequences via Threading Polyintercalation
[Image: see text] Small molecules that bind DNA in a sequence-specific manner could act as antibiotic, antiviral, or anticancer agents because of their potential ability to manipulate gene expression. Our laboratory has developed threading polyintercalators based on 1,4,5,8-naphthalene diimide (NDI)...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369501/ https://www.ncbi.nlm.nih.gov/pubmed/22554127 http://dx.doi.org/10.1021/bi300317n |