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Therapy Development for Spinal Muscular Atrophy in SMN Independent Targets

Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disorder, leading to progressive muscle weakness, atrophy, and sometimes premature death. SMA is caused by mutation or deletion of the survival motor neuron-1 (SMN1) gene. An effective treatment does not presently exist. Since...

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Detalles Bibliográficos
Autor principal:	Tsai, Li-Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369530/ https://www.ncbi.nlm.nih.gov/pubmed/22701806 http://dx.doi.org/10.1155/2012/456478

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