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Keratin 8/18 Regulation of Cell Stiffness-Extracellular Matrix Interplay through Modulation of Rho-Mediated Actin Cytoskeleton Dynamics

Cell mechanical activity generated from the interplay between the extracellular matrix (ECM) and the actin cytoskeleton is essential for the regulation of cell adhesion, spreading and migration during normal and cancer development. Keratins are the intermediate filament (IF) proteins of epithelial c...

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Detalles Bibliográficos
Autores principales: Bordeleau, François, Myrand Lapierre, Marie-Eve, Sheng, Yunlong, Marceau, Normand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369864/
https://www.ncbi.nlm.nih.gov/pubmed/22685604
http://dx.doi.org/10.1371/journal.pone.0038780