A Coevolutionary Residue Network at the Site of a Functionally Important Conformational Change in a Phosphohexomutase Enzyme Family

Coevolution analyses identify residues that co-vary with each other during evolution, revealing sequence relationships unobservable from traditional multiple sequence alignments. Here we describe a coevolutionary analysis of phosphomannomutase/phosphoglucomutase (PMM/PGM), a widespread and diverse e...

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Detalles Bibliográficos
Autores principales: Lee, Yingying, Mick, Jacob, Furdui, Cristina, Beamer, Lesa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369874/
https://www.ncbi.nlm.nih.gov/pubmed/22685552
http://dx.doi.org/10.1371/journal.pone.0038114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369874/
https://www.ncbi.nlm.nih.gov/pubmed/22685552
http://dx.doi.org/10.1371/journal.pone.0038114

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