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A Coevolutionary Residue Network at the Site of a Functionally Important Conformational Change in a Phosphohexomutase Enzyme Family
Coevolution analyses identify residues that co-vary with each other during evolution, revealing sequence relationships unobservable from traditional multiple sequence alignments. Here we describe a coevolutionary analysis of phosphomannomutase/phosphoglucomutase (PMM/PGM), a widespread and diverse e...
Autores principales: | Lee, Yingying, Mick, Jacob, Furdui, Cristina, Beamer, Lesa J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369874/ https://www.ncbi.nlm.nih.gov/pubmed/22685552 http://dx.doi.org/10.1371/journal.pone.0038114 |
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