Protein Disulfide Isomerase Regulates Endoplasmic Reticulum Stress and the Apoptotic Process during Prion Infection and PrP Mutant-Induced Cytotoxicity

BACKGROUND: Protein disulfide isomerase (PDI), is sorted to be enzymatic chaperone for reconstructing misfolded protein in endoplasmic reticulum lumen. Recently, PDI has been identified as a link between misfolded protein and neuron apoptosis. However, the potential for PDI to be involved in the pat...

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Detalles Bibliográficos
Autores principales: Wang, Shao-Bin, Shi, Qi, Xu, Yin, Xie, Wu-Ling, Zhang, Jin, Tian, Chan, Guo, Yan, Wang, Ke, Zhang, Bao-Yun, Chen, Cao, Gao, Chen, Dong, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369880/
https://www.ncbi.nlm.nih.gov/pubmed/22685557
http://dx.doi.org/10.1371/journal.pone.0038221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369880/
https://www.ncbi.nlm.nih.gov/pubmed/22685557
http://dx.doi.org/10.1371/journal.pone.0038221

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