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Protein Disulfide Isomerase Regulates Endoplasmic Reticulum Stress and the Apoptotic Process during Prion Infection and PrP Mutant-Induced Cytotoxicity
BACKGROUND: Protein disulfide isomerase (PDI), is sorted to be enzymatic chaperone for reconstructing misfolded protein in endoplasmic reticulum lumen. Recently, PDI has been identified as a link between misfolded protein and neuron apoptosis. However, the potential for PDI to be involved in the pat...
Autores principales: | Wang, Shao-Bin, Shi, Qi, Xu, Yin, Xie, Wu-Ling, Zhang, Jin, Tian, Chan, Guo, Yan, Wang, Ke, Zhang, Bao-Yun, Chen, Cao, Gao, Chen, Dong, Xiao-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369880/ https://www.ncbi.nlm.nih.gov/pubmed/22685557 http://dx.doi.org/10.1371/journal.pone.0038221 |
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