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Recruitment of Histone Deacetylase 3 to the Interferon-A Gene Promoters Attenuates Interferon Expression

BACKGROUND: Induction of Type I Interferon (IFN) genes constitutes an essential step leading to innate immune responses during virus infection. Sendai virus (SeV) infection of B lymphoid Namalwa cells transiently induces the transcriptional expression of multiple IFN-A genes. Although transcriptiona...

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Detalles Bibliográficos
Autores principales: Génin, Pierre, Lin, Rongtuan, Hiscott, John, Civas, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369917/
https://www.ncbi.nlm.nih.gov/pubmed/22685561
http://dx.doi.org/10.1371/journal.pone.0038336