TRAM Is Involved in IL-18 Signaling and Functions as a Sorting Adaptor for MyD88

MyD88, a Toll/interleukin-1 receptor homology (TIR) domain-containing adaptor protein, mediates signals from the Toll-like receptors (TLR) or IL-1/IL-18 receptors to downstream kinases. In MyD88-dependent TLR4 signaling, the function of MyD88 is enhanced by another TIR domain-containing adaptor, Mal...

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Detalles Bibliográficos
Autores principales: Ohnishi, Hidenori, Tochio, Hidehito, Kato, Zenichiro, Kawamoto, Norio, Kimura, Takeshi, Kubota, Kazuo, Yamamoto, Takahiro, Funasaka, Tatsuyoshi, Nakano, Hiroshi, Wong, Richard W., Shirakawa, Masahiro, Kondo, Naomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369926/
https://www.ncbi.nlm.nih.gov/pubmed/22685567
http://dx.doi.org/10.1371/journal.pone.0038423

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