Cargando…

Effector CD4+ T Cell Expression Signatures and Immune-Mediated Disease Associated Genes

Genome-wide association studies (GWAS) in immune-mediated diseases have identified over 150 associated genomic loci. Many of these loci play a role in T cell responses, and regulation of T cell differentiation plays a critical role in immune-mediated diseases; however, the relationship between impli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Wei, Ferguson, John, Ng, Sok Meng, Hui, Ken, Goh, Gerald, Lin, Aiping, Esplugues, Enric, Flavell, Richard A., Abraham, Clara, Zhao, Hongyu, Cho, Judy H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371029/ https://www.ncbi.nlm.nih.gov/pubmed/22715389 http://dx.doi.org/10.1371/journal.pone.0038510

Ejemplares similares

Enhanced Antitumor Immunity in Mice Deficient in CD69
por: Esplugues, Enric, et al.
Publicado: (2003)

Apoptosis in response to microbial infection induces autoreactive T(H)17 cells
por: Campisi, Laura, et al.
Publicado: (2016)

Follicular helper T cells progressively differentiate to regulate the germinal center response
por: Weinstein, Jason S., et al.
Publicado: (2016)

Granzyme B + CD8 + T cells with terminal differentiated effector signature determine multiple sclerosis progression
por: Shi, Ziyan, et al.
Publicado: (2023)

Age and CD161 Expression Contribute to Inter-Individual Variation in Interleukin-23 Response in CD8+ Memory Human T Cells
por: Shen, Hui, et al.
Publicado: (2013)

The Role of T(H)17-Associated Cytokines in Health and Disease
por: O'Connor, William, et al.
Publicado: (2014)

Regulation of CD4(+) and CD8(+) Effector Responses by Sprouty-1
por: Collins, Sam, et al.
Publicado: (2012)

Pathway analysis comparison using Crohn's disease genome wide association studies
por: Ballard, David, et al.
Publicado: (2010)

Cytotoxic CD4(+) T cells in cancer: Expanding the immune effector toolbox
por: Oh, David Y., et al.
Publicado: (2021)

Mitochondrial Dysfunction in CD4+ T Effector Memory RA+ Cells
por: Strickland, Marie, et al.
Publicado: (2023)

NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8(+) T Cells
por: Gupta, Shubhranshu S., et al.
Publicado: (2019)

Salmonella Typhimurium Type III Secretion Effectors Stimulate Innate Immune Responses in Cultured Epithelial Cells
por: Bruno, Vincent M., et al.
Publicado: (2009)

Protective Effector Memory CD4 T Cells Depend on ICOS for Survival
por: Moore, Tamson V., et al.
Publicado: (2011)

Effector Memory CD8(+) and CD4(+) T Cell Immunity Associated with Metabolic Syndrome in Obese Children
por: Yang, Da-Hee, et al.
Publicado: (2021)

Effector, Memory, and Dysfunctional CD8(+) T Cell Fates in the Antitumor Immune Response
por: Reiser, John, et al.
Publicado: (2016)

CD4(+) cytotoxic T cells: an emerging effector arm of anti-tumor immunity
por: Jeong, Seongmin, et al.
Publicado: (2023)

CD25-T(reg)-depleting antibodies preserving IL-2 signaling on effector T cells enhance effector activation and antitumor immunity
por: Solomon, Isabelle, et al.
Publicado: (2020)

Memory/effector (CD45RB(lo)) CD4 T cells are controlled directly by IL-10 and cause IL-22–dependent intestinal pathology
por: Kamanaka, Masahito, et al.
Publicado: (2011)

Effector triggered immunity: Activation of innate immunity in metazoans by bacterial effectors
por: Rajamuthiah, Rajmohan, et al.
Publicado: (2014)

Tumor Infiltrating Effector Memory Antigen-Specific CD8(+) T Cells Predict Response to Immune Checkpoint Therapy
por: Principe, Nicola, et al.
Publicado: (2020)

Legionella pneumophila Strain 130b Evades Macrophage Cell Death Independent of the Effector SidF in the Absence of Flagellin
por: Speir, Mary, et al.
Publicado: (2017)

Prognostic Immune Effector Signature in Adult Acute Lymphoblastic Leukemia Patients Is Dominated by γδ T Cells
por: Le Floch, Anne-Charlotte, et al.
Publicado: (2023)

The endosome as an effector target to mediate plant immunity?
por: Reilly, Aisling, et al.
Publicado: (2022)

CD200–CD200R immune checkpoint engagement regulates ILC2 effector function and ameliorates lung inflammation in asthma
por: Shafiei-Jahani, Pedram, et al.
Publicado: (2021)

CD47(Low) Status on CD4 Effectors Is Necessary for the Contraction/Resolution of the Immune Response in Humans and Mice
por: Van, Vu Quang, et al.
Publicado: (2012)

BCL6 deletion in CD4 T cells does not affect Th2 effector mediated immunity in the skin
por: Chandler, Jodie, et al.
Publicado: (2022)

T cell sensitivity to TGF-β is required for the effector function but not the generation of splenic CD8(+) regulatory T cells induced via the injection of antigen into the anterior chamber
por: Cone, Robert E., et al.
Publicado: (2009)

Heterogeneity of human effector CD4(+ )T cells
por: Annunziato, Francesco, et al.
Publicado: (2009)

CD90(+) Stromal Cells are Non-Professional Innate Immune Effectors of the Human Colonic Mucosa
por: Owens, Benjamin M. J., et al.
Publicado: (2013)

Distinct Immune Profiles of Exhausted Effector and Memory CD8(+) T Cells in Individuals With Filarial Lymphedema
por: Horn, Sacha, et al.
Publicado: (2021)

Protein Tyrosine Phosphatase CD45 As an Immunity Regulator and a Potential Effector of CAR-T therapy
por: Volkov, D. V., et al.
Publicado: (2023)

Expanded antigen-experienced CD160(+)CD8(+)effector T cells exhibit impaired effector functions in chronic lymphocytic leukemia
por: Bozorgmehr, Najmeh, et al.
Publicado: (2021)

Effector CD4 and CD8 T Cells and Their Role in the Tumor Microenvironment
por: Hadrup, Sine, et al.
Publicado: (2012)

Distinct Effector Memory CD4(+) T Cell Signatures in Latent Mycobacterium tuberculosis Infection, BCG Vaccination and Clinically Resolved Tuberculosis
por: Adekambi, Toidi, et al.
Publicado: (2012)

Bcl6 expression specifies the T follicular helper cell program in vivo
por: Liu, Xindong, et al.
Publicado: (2012)

Protection by and maintenance of CD4 effector memory and effector T cell subsets in persistent malaria infection
por: Opata, Michael M., et al.
Publicado: (2018)

GOT1 regulates CD8(+) effector and memory T cell generation
por: Xu, Wei, et al.
Publicado: (2023)

Immune signatures of protective spleen memory CD8 T cells
por: Brinza, Lilia, et al.
Publicado: (2016)

CD8(+) T Cell–mediated Injury In Vivo Progresses in the Absence of Effector T Cells
por: Small, Barbara A., et al.
Publicado: (2001)

Effector CD4 T cells with progenitor potential mediate chronic intestinal inflammation
por: Shin, Boyoung, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_u9qc71nfue8nv296ug81594t2q