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Gentamicin Rapidly Inhibits Mitochondrial Metabolism in High-Frequency Cochlear Outer Hair Cells

Aminoglycosides (AG), including gentamicin (GM), are the most frequently used antibiotics in the world and are proposed to cause irreversible cochlear damage and hearing loss (HL) in 1/4 of the patients receiving these life-saving drugs. Akin to the results of AG ototoxicity studies, high-frequency,...

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Detalles Bibliográficos
Autores principales:	Jensen-Smith, Heather C., Hallworth, Richard, Nichols, Michael G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371036/ https://www.ncbi.nlm.nih.gov/pubmed/22715386 http://dx.doi.org/10.1371/journal.pone.0038471

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