Seroconversion of Hepatitis B Envelope Antigen (HBeAg) by Entecavir in a Child with Chronic Hepatitis B

Hepatitis B virus (HBV) infection is a worldwide health problem. Consensus guidelines for the treatment of chronic HBV in children have not been established, and indications for antiviral therapy in adults with chronic HBV infection may not be applicable to children. The medications that are Food an...

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Autores principales: Hasosah, Mohammed Y., Ghandourah, Heba S., Alsahafi, Ashraf F., Sukkar, Ghassan A., Jacobson, Kevan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371426/
https://www.ncbi.nlm.nih.gov/pubmed/22626803
http://dx.doi.org/10.4103/1319-3767.96465
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author Hasosah, Mohammed Y.
Ghandourah, Heba S.
Alsahafi, Ashraf F.
Sukkar, Ghassan A.
Jacobson, Kevan
author_facet Hasosah, Mohammed Y.
Ghandourah, Heba S.
Alsahafi, Ashraf F.
Sukkar, Ghassan A.
Jacobson, Kevan
author_sort Hasosah, Mohammed Y.
collection PubMed
description Hepatitis B virus (HBV) infection is a worldwide health problem. Consensus guidelines for the treatment of chronic HBV in children have not been established, and indications for antiviral therapy in adults with chronic HBV infection may not be applicable to children. The medications that are Food and Drug Administration approved for the treatment of children with HBV include interferon (IFN)-alpha and lamivudine. Nondetectable serum HBV deoxyribonucleic acid, Hepatitis B envelope antigen (HBeAg) loss, and HBeAg seroconversion following 1 year duration of entecavir treatment. A review of the literature of entecavir treatment of chronic hepatitis B in children is also provided.
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spelling pubmed-33714262012-06-13 Seroconversion of Hepatitis B Envelope Antigen (HBeAg) by Entecavir in a Child with Chronic Hepatitis B Hasosah, Mohammed Y. Ghandourah, Heba S. Alsahafi, Ashraf F. Sukkar, Ghassan A. Jacobson, Kevan Saudi J Gastroenterol Case Report Hepatitis B virus (HBV) infection is a worldwide health problem. Consensus guidelines for the treatment of chronic HBV in children have not been established, and indications for antiviral therapy in adults with chronic HBV infection may not be applicable to children. The medications that are Food and Drug Administration approved for the treatment of children with HBV include interferon (IFN)-alpha and lamivudine. Nondetectable serum HBV deoxyribonucleic acid, Hepatitis B envelope antigen (HBeAg) loss, and HBeAg seroconversion following 1 year duration of entecavir treatment. A review of the literature of entecavir treatment of chronic hepatitis B in children is also provided. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3371426/ /pubmed/22626803 http://dx.doi.org/10.4103/1319-3767.96465 Text en Copyright: © Saudi Journal of Gastroenterology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Hasosah, Mohammed Y.
Ghandourah, Heba S.
Alsahafi, Ashraf F.
Sukkar, Ghassan A.
Jacobson, Kevan
Seroconversion of Hepatitis B Envelope Antigen (HBeAg) by Entecavir in a Child with Chronic Hepatitis B
title Seroconversion of Hepatitis B Envelope Antigen (HBeAg) by Entecavir in a Child with Chronic Hepatitis B
title_full Seroconversion of Hepatitis B Envelope Antigen (HBeAg) by Entecavir in a Child with Chronic Hepatitis B
title_fullStr Seroconversion of Hepatitis B Envelope Antigen (HBeAg) by Entecavir in a Child with Chronic Hepatitis B
title_full_unstemmed Seroconversion of Hepatitis B Envelope Antigen (HBeAg) by Entecavir in a Child with Chronic Hepatitis B
title_short Seroconversion of Hepatitis B Envelope Antigen (HBeAg) by Entecavir in a Child with Chronic Hepatitis B
title_sort seroconversion of hepatitis b envelope antigen (hbeag) by entecavir in a child with chronic hepatitis b
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371426/
https://www.ncbi.nlm.nih.gov/pubmed/22626803
http://dx.doi.org/10.4103/1319-3767.96465
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