Fast MCMC sampling for hidden markov models to determine copy number variations

BACKGROUND: Hidden Markov Models (HMM) are often used for analyzing Comparative Genomic Hybridization (CGH) data to identify chromosomal aberrations or copy number variations by segmenting observation sequences. For efficiency reasons the parameters of a HMM are often estimated with maximum likeliho...

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Detalles Bibliográficos
Autores principales: Mahmud, Md Pavel, Schliep, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371636/
https://www.ncbi.nlm.nih.gov/pubmed/22047014
http://dx.doi.org/10.1186/1471-2105-12-428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371636/
https://www.ncbi.nlm.nih.gov/pubmed/22047014
http://dx.doi.org/10.1186/1471-2105-12-428

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