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A systematic study of gene expression variation at single-nucleotide resolution reveals widespread regulatory roles for uAUGs

Regulatory single-nucleotide polymorphisms (rSNPs) alter gene expression. Common approaches for identifying rSNPs focus on sequence variants in conserved regions; however, it is unknown what fraction of rSNPs is undetectable using this approach. We present a systematic analysis of gene expression va...

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Detalles Bibliográficos
Autores principales: Yun, Yue, Adesanya, T.M. Ayodele, Mitra, Robi D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371711/
https://www.ncbi.nlm.nih.gov/pubmed/22454232
http://dx.doi.org/10.1101/gr.117366.110