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Exploring Short-Term Responses to Changes in the Control Strategy for Chlamydia trachomatis
Chlamydia has a significant impact on public health provision in the developed world. Using pair approximation equations we investigate the efficacy of control programmes for chlamydia on short time scales that are relevant to policy makers. We use output from the model to estimate critical measures...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371724/ https://www.ncbi.nlm.nih.gov/pubmed/22701143 http://dx.doi.org/10.1155/2012/803097 |
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author | Clarke, James White, K. A. Jane Turner, Katy |
author_facet | Clarke, James White, K. A. Jane Turner, Katy |
author_sort | Clarke, James |
collection | PubMed |
description | Chlamydia has a significant impact on public health provision in the developed world. Using pair approximation equations we investigate the efficacy of control programmes for chlamydia on short time scales that are relevant to policy makers. We use output from the model to estimate critical measures, namely, prevalence, incidence, and positivity in those screened and their partners. We combine these measures with a costing tool to estimate the economic impact of different public health strategies. Increasing screening coverage significantly increases the annual programme costs whereas an increase in tracing efficiency initially increases annual costs but over time reduces costs below baseline, with tracing accounting for around 10% of intervention costs. We found that partner positivity is insensitive to changes in prevalence due to screening, remaining at around 33%. Whether increases occur in screening or tracing levels, the cost per treated infection increases from the baseline because of reduced prevalence. |
format | Online Article Text |
id | pubmed-3371724 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-33717242012-06-13 Exploring Short-Term Responses to Changes in the Control Strategy for Chlamydia trachomatis Clarke, James White, K. A. Jane Turner, Katy Comput Math Methods Med Research Article Chlamydia has a significant impact on public health provision in the developed world. Using pair approximation equations we investigate the efficacy of control programmes for chlamydia on short time scales that are relevant to policy makers. We use output from the model to estimate critical measures, namely, prevalence, incidence, and positivity in those screened and their partners. We combine these measures with a costing tool to estimate the economic impact of different public health strategies. Increasing screening coverage significantly increases the annual programme costs whereas an increase in tracing efficiency initially increases annual costs but over time reduces costs below baseline, with tracing accounting for around 10% of intervention costs. We found that partner positivity is insensitive to changes in prevalence due to screening, remaining at around 33%. Whether increases occur in screening or tracing levels, the cost per treated infection increases from the baseline because of reduced prevalence. Hindawi Publishing Corporation 2012 2012-06-03 /pmc/articles/PMC3371724/ /pubmed/22701143 http://dx.doi.org/10.1155/2012/803097 Text en Copyright © 2012 James Clarke et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Clarke, James White, K. A. Jane Turner, Katy Exploring Short-Term Responses to Changes in the Control Strategy for Chlamydia trachomatis |
title | Exploring Short-Term Responses to Changes in the Control Strategy for Chlamydia trachomatis
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title_full | Exploring Short-Term Responses to Changes in the Control Strategy for Chlamydia trachomatis
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title_fullStr | Exploring Short-Term Responses to Changes in the Control Strategy for Chlamydia trachomatis
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title_full_unstemmed | Exploring Short-Term Responses to Changes in the Control Strategy for Chlamydia trachomatis
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title_short | Exploring Short-Term Responses to Changes in the Control Strategy for Chlamydia trachomatis
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title_sort | exploring short-term responses to changes in the control strategy for chlamydia trachomatis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371724/ https://www.ncbi.nlm.nih.gov/pubmed/22701143 http://dx.doi.org/10.1155/2012/803097 |
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