Cargando…
Female mouse fetal loss mediated by maternal autoantibody
Systemic lupus erythematosus (SLE), a disease of women during childbearing years, is characterized by the production of double-stranded DNA antibodies. A subset of these antibodies, present in 40% of patients, cross-reacts with the NR2A and NR2B subunits of the N-methyl-d-aspartate receptor (NMDAR)....
Autores principales: | Wang, Li, Zhou, Dun, Lee, Ji, Niu, Haitao, Faust, Thomas W., Frattini, Stephen, Kowal, Czeslawa, Huerta, Patricio T., Volpe, Bruce T., Diamond, Betty |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371726/ https://www.ncbi.nlm.nih.gov/pubmed/22565825 http://dx.doi.org/10.1084/jem.20111986 |
Ejemplares similares
-
Maternal lupus and congenital cortical impairment
por: Lee, Ji Y., et al.
Publicado: (2008) -
XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development
por: Todd, Derrick J., et al.
Publicado: (2009) -
Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory
por: Chan, Kelvin, et al.
Publicado: (2020) -
Selective Impairment of Spatial Cognition Caused by Autoantibodies to the N-Methyl-d-Aspartate Receptor
por: Chang, Eric H., et al.
Publicado: (2015) -
Regional brain metabolism in a murine systemic lupus erythematosus model
por: Vo, An, et al.
Publicado: (2014)