Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization

Llamas (Lama glama) naturally produce heavy chain–only antibodies (Abs) in addition to conventional Abs. The variable regions (VHH) in these heavy chain–only Abs demonstrate comparable affinity and specificity for antigens to conventional immunoglobulins despite their much smaller size. To date, imm...

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Detalles Bibliográficos
Autores principales: McCoy, Laura E., Quigley, Anna Forsman, Strokappe, Nika M., Bulmer-Thomas, Bianca, Seaman, Michael S., Mortier, Daniella, Rutten, Lucy, Chander, Nikita, Edwards, Carolyn J., Ketteler, Robin, Davis, David, Verrips, Theo, Weiss, Robin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371729/
https://www.ncbi.nlm.nih.gov/pubmed/22641382
http://dx.doi.org/10.1084/jem.20112655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371729/
https://www.ncbi.nlm.nih.gov/pubmed/22641382
http://dx.doi.org/10.1084/jem.20112655

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