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Unstressing intemperate models: how cold stress undermines mouse modeling
Mus musculus enjoys pride of place at the center of contemporary biomedical research. Despite being the current model system of choice for in vivo mechanistic analysis, mice have clear limitations. The literature is littered with examples of therapeutic approaches that showed promise in mouse models...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Rockefeller University Press
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371737/ https://www.ncbi.nlm.nih.gov/pubmed/22665703 http://dx.doi.org/10.1084/jem.20120988 |