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Antibacterial Susceptibility Patterns and Cross-Resistance of Acinetobacter, Isolated from Hospitalized Patients, Southern Iran

BACKGROUND: Acinetobacter is a multi-drug resistant and nosocomial pathogen. The aim of this study was to determine antibacterial susceptibility patterns and cross-resistance of Acinetobacter species. METHODS: This study was conducted in Nemazee Hospital, Shiraz, Iran from October 2007 to September...

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Autores principales: Japoni, S, Farshad, S, Abdi Ali, A, Japoni, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371892/
https://www.ncbi.nlm.nih.gov/pubmed/22737424
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author Japoni, S
Farshad, S
Abdi Ali, A
Japoni, A
author_facet Japoni, S
Farshad, S
Abdi Ali, A
Japoni, A
author_sort Japoni, S
collection PubMed
description BACKGROUND: Acinetobacter is a multi-drug resistant and nosocomial pathogen. The aim of this study was to determine antibacterial susceptibility patterns and cross-resistance of Acinetobacter species. METHODS: This study was conducted in Nemazee Hospital, Shiraz, Iran from October 2007 to September 2008. Species identification was carried out by API E20. Minimum inhibitory concentration and cross-resistance of the isolated strains to 12 antibiotics were determined by E-test method. RESULTS: Eighty eight isolates of Acinetobacter were collected from patients’ samples. Acinetobacter baumannii was isolated most frequently (79; 89.8%). Colistin, imipenem and meropenem were found to be the three most effective antibiotics with 97.7%, 77.3% and 72.7% activity against the isolates, respectively. Multi-drug resistance was revealed among 2 to 11 antibiotics and high cross-resistance was also noticed. CONCLUSION: To alleviate the situation, strict control measures and appropriate effective antibiotic therapy should be adopted to reduce hospital costs and related mortality.
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spelling pubmed-33718922012-06-21 Antibacterial Susceptibility Patterns and Cross-Resistance of Acinetobacter, Isolated from Hospitalized Patients, Southern Iran Japoni, S Farshad, S Abdi Ali, A Japoni, A Iran Red Crescent Med J Short Communication BACKGROUND: Acinetobacter is a multi-drug resistant and nosocomial pathogen. The aim of this study was to determine antibacterial susceptibility patterns and cross-resistance of Acinetobacter species. METHODS: This study was conducted in Nemazee Hospital, Shiraz, Iran from October 2007 to September 2008. Species identification was carried out by API E20. Minimum inhibitory concentration and cross-resistance of the isolated strains to 12 antibiotics were determined by E-test method. RESULTS: Eighty eight isolates of Acinetobacter were collected from patients’ samples. Acinetobacter baumannii was isolated most frequently (79; 89.8%). Colistin, imipenem and meropenem were found to be the three most effective antibiotics with 97.7%, 77.3% and 72.7% activity against the isolates, respectively. Multi-drug resistance was revealed among 2 to 11 antibiotics and high cross-resistance was also noticed. CONCLUSION: To alleviate the situation, strict control measures and appropriate effective antibiotic therapy should be adopted to reduce hospital costs and related mortality. Kowsar 2011-11 2011-11-01 /pmc/articles/PMC3371892/ /pubmed/22737424 Text en Copyright © 2011, Kowsar Corp. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Japoni, S
Farshad, S
Abdi Ali, A
Japoni, A
Antibacterial Susceptibility Patterns and Cross-Resistance of Acinetobacter, Isolated from Hospitalized Patients, Southern Iran
title Antibacterial Susceptibility Patterns and Cross-Resistance of Acinetobacter, Isolated from Hospitalized Patients, Southern Iran
title_full Antibacterial Susceptibility Patterns and Cross-Resistance of Acinetobacter, Isolated from Hospitalized Patients, Southern Iran
title_fullStr Antibacterial Susceptibility Patterns and Cross-Resistance of Acinetobacter, Isolated from Hospitalized Patients, Southern Iran
title_full_unstemmed Antibacterial Susceptibility Patterns and Cross-Resistance of Acinetobacter, Isolated from Hospitalized Patients, Southern Iran
title_short Antibacterial Susceptibility Patterns and Cross-Resistance of Acinetobacter, Isolated from Hospitalized Patients, Southern Iran
title_sort antibacterial susceptibility patterns and cross-resistance of acinetobacter, isolated from hospitalized patients, southern iran
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371892/
https://www.ncbi.nlm.nih.gov/pubmed/22737424
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