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The Effect of Fig Tree Latex (Ficus carica) on Stomach Cancer Line

BACKGROUND: The therapeutic effect of herbal materials in inhibition of cancer cell growth was shown. This study investigates the effect of fig tree latex (Ficus carica) on stomach cancer line. METHODS: The in vitro effect of different doses of fig tree latex on stomach cancer cell line and the peri...

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Detalles Bibliográficos
Autores principales: Hashemi, S A, Abediankenari, S, Ghasemi, M, Azadbakht, M, Yousefzadeh, Y, Dehpour, A A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371962/
https://www.ncbi.nlm.nih.gov/pubmed/22737478
Descripción
Sumario:BACKGROUND: The therapeutic effect of herbal materials in inhibition of cancer cell growth was shown. This study investigates the effect of fig tree latex (Ficus carica) on stomach cancer line. METHODS: The in vitro effect of different doses of fig tree latex on stomach cancer cell line and the peripheral blood mononuclear cells was evaluated after 72 hours. RESULTS: Fig tree latex could inhibit the proliferation of cancer cell line without any cytotoxic effect on human normal cells. Five mg/ml was the optimum concentration in inhibition of cell line growth. CONCLUSION: Cancer cell line was more sensitive to Ficus carica latex than normal cells. This anticancer activity might be due to presence of its proteolytic enzymes.