The Effect of Fig Tree Latex (Ficus carica) on Stomach Cancer Line

BACKGROUND: The therapeutic effect of herbal materials in inhibition of cancer cell growth was shown. This study investigates the effect of fig tree latex (Ficus carica) on stomach cancer line. METHODS: The in vitro effect of different doses of fig tree latex on stomach cancer cell line and the peri...

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Detalles Bibliográficos
Autores principales: Hashemi, S A, Abediankenari, S, Ghasemi, M, Azadbakht, M, Yousefzadeh, Y, Dehpour, A A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2011
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371962/
https://www.ncbi.nlm.nih.gov/pubmed/22737478
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author Hashemi, S A
Abediankenari, S
Ghasemi, M
Azadbakht, M
Yousefzadeh, Y
Dehpour, A A
author_facet Hashemi, S A
Abediankenari, S
Ghasemi, M
Azadbakht, M
Yousefzadeh, Y
Dehpour, A A
author_sort Hashemi, S A
collection PubMed
description BACKGROUND: The therapeutic effect of herbal materials in inhibition of cancer cell growth was shown. This study investigates the effect of fig tree latex (Ficus carica) on stomach cancer line. METHODS: The in vitro effect of different doses of fig tree latex on stomach cancer cell line and the peripheral blood mononuclear cells was evaluated after 72 hours. RESULTS: Fig tree latex could inhibit the proliferation of cancer cell line without any cytotoxic effect on human normal cells. Five mg/ml was the optimum concentration in inhibition of cell line growth. CONCLUSION: Cancer cell line was more sensitive to Ficus carica latex than normal cells. This anticancer activity might be due to presence of its proteolytic enzymes.
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spelling pubmed-33719622012-06-21 The Effect of Fig Tree Latex (Ficus carica) on Stomach Cancer Line Hashemi, S A Abediankenari, S Ghasemi, M Azadbakht, M Yousefzadeh, Y Dehpour, A A Iran Red Crescent Med J Short Communication BACKGROUND: The therapeutic effect of herbal materials in inhibition of cancer cell growth was shown. This study investigates the effect of fig tree latex (Ficus carica) on stomach cancer line. METHODS: The in vitro effect of different doses of fig tree latex on stomach cancer cell line and the peripheral blood mononuclear cells was evaluated after 72 hours. RESULTS: Fig tree latex could inhibit the proliferation of cancer cell line without any cytotoxic effect on human normal cells. Five mg/ml was the optimum concentration in inhibition of cell line growth. CONCLUSION: Cancer cell line was more sensitive to Ficus carica latex than normal cells. This anticancer activity might be due to presence of its proteolytic enzymes. Kowsar 2011-04 2011-04-01 /pmc/articles/PMC3371962/ /pubmed/22737478 Text en Copyright © 2011, Kowsar M.P. Co. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Hashemi, S A
Abediankenari, S
Ghasemi, M
Azadbakht, M
Yousefzadeh, Y
Dehpour, A A
The Effect of Fig Tree Latex (Ficus carica) on Stomach Cancer Line
title The Effect of Fig Tree Latex (Ficus carica) on Stomach Cancer Line
title_full The Effect of Fig Tree Latex (Ficus carica) on Stomach Cancer Line
title_fullStr The Effect of Fig Tree Latex (Ficus carica) on Stomach Cancer Line
title_full_unstemmed The Effect of Fig Tree Latex (Ficus carica) on Stomach Cancer Line
title_short The Effect of Fig Tree Latex (Ficus carica) on Stomach Cancer Line
title_sort effect of fig tree latex (ficus carica) on stomach cancer line
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371962/
https://www.ncbi.nlm.nih.gov/pubmed/22737478
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