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Acidosis Differentially Modulates Inactivation in Na(V)1.2, Na(V)1.4, and Na(V)1.5 Channels

Na(V) channels play a crucial role in neuronal and muscle excitability. Using whole-cell recordings we studied effects of low extracellular pH on the biophysical properties of Na(V)1.2, Na(V)1.4, and Na(V)1.5, expressed in cultured mammalian cells. Low pH produced different effects on different chan...

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Detalles Bibliográficos
Autores principales:	Vilin, Yury Y., Peters, Colin H., Ruben, Peter C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372088/ https://www.ncbi.nlm.nih.gov/pubmed/22701426 http://dx.doi.org/10.3389/fphar.2012.00109

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