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Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks

BACKGROUND: Age-related macular degeneration (AMD) is a leading cause of blindness that affects the central region of the retinal pigmented epithelium (RPE), choroid, and neural retina. Initially characterized by an accumulation of sub-RPE deposits, AMD leads to progressive retinal degeneration, and...

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Detalles Bibliográficos
Autores principales:	Newman, Aaron M, Gallo, Natasha B, Hancox, Lisa S, Miller, Norma J, Radeke, Carolyn M, Maloney, Michelle A, Cooper, James B, Hageman, Gregory S, Anderson, Don H, Johnson, Lincoln V, Radeke, Monte J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372225/ https://www.ncbi.nlm.nih.gov/pubmed/22364233 http://dx.doi.org/10.1186/gm315

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